Synthesis and characterization of BODIPY-labeled colchicineARNOLD, Leggy A; RANAIVO, Patricia; KIPLIN GUY, R et al.Bioorganic & medicinal chemistry letters (Print). 2008, Vol 18, Num 22, pp 5867-5870, issn 0960-894X, 4 p.Article

A road less traveled by : Exploring a decade of Ellman chemistry : Tetrahedron Young Investigator Award 2004SHELAT, Anang A; KIPLIN GUY, R.Bioorganic & medicinal chemistry. 2009, Vol 17, Num 3, pp 1088-1093, issn 0968-0896, 6 p.Article

Synthesis of highly substituted dibenzo[b,f]azocines and their evaluation as protein kinase inhibitorsARNOLD, Leggy A; KIPLIN GUY, R.Bioorganic & medicinal chemistry letters (Print). 2006, Vol 16, Num 20, pp 5360-5363, issn 0960-894X, 4 p.Article

Antimalarial activity of thiosemicarbazones and purine derived nitrilesMALLARI, Jeremy P; GUIGUEMDE, Wendyam A; KIPLIN GUY, R et al.Bioorganic & medicinal chemistry letters (Print). 2009, Vol 19, Num 13, pp 3546-3549, issn 0960-894X, 4 p.Article

Design of a selective chemical probe for class I PDZ domainsFUJII, Naoaki; SHELAT, Anang; HALL, Randy A et al.Bioorganic & medicinal chemistry letters (Print). 2007, Vol 17, Num 2, pp 546-548, issn 0960-894X, 3 p.Article

A solid-phase approach to the phallotoxins : Total synthesis of [Ala⁷]-phalloidinANDERSON, Marc O; SHELAT, Anang A; KIPLIN GUY, R et al.Journal of organic chemistry. 2005, Vol 70, Num 12, pp 4578-4584, issn 0022-3263, 7 p.Article

Incorporation of an intramolecular hydrogen-bonding motif in the side chain of 4-aminoquinolines enhances activity against drug-resistant P. falciparumMADRID, Peter B; LIOU, Ally P; DERISI, Joseph L et al.Journal of medicinal chemistry (Print). 2006, Vol 49, Num 15, pp 4535-4543, issn 0022-2623, 9 p.Article

Inhibitors of the interaction of a thyroid hormone receptor and coactivators : Preliminary structure-activity relationshipsARNOLD, Leggy A; KOSINSKI, Aaron; ESTEBANEZ-PERPINA, Eva et al.Journal of medicinal chemistry (Print). 2007, Vol 50, Num 22, pp 5269-5280, issn 0022-2623, 12 p.Article

Optimization of purine-nitrile TbcatB inhibitors for use in vivo and evaluation of efficacy in murine modelsMALLARI, Jeremy P; FANGYI ZHU; LEMOFF, Andrew et al.Bioorganic & medicinal chemistry. 2010, Vol 18, Num 23, pp 8302-8309, issn 0968-0896, 8 p.Article

Podophyllotoxin analogues active versus Trypanosoma bruceiJASHIM UDDIN, Md; SMITHSON, David C; BROWN, Kristin M et al.Bioorganic & medicinal chemistry letters (Print). 2010, Vol 20, Num 5, pp 1787-1791, issn 0960-894X, 5 p.Article

An antagonist of dishevelled protein-protein interaction suppresses β-catenin-dependent tumor cell growthFUJII, Naoaki; LIANG YOU; KIPLIN GUY, R et al.Cancer research (Baltimore). 2007, Vol 67, Num 2, pp 573-579, issn 0008-5472, 7 p.Article

Discovery of trypanocidal thiosemicarbazone inhibitors of rhodesain and TbcatBMALLARI, Jeremy P; SHELAT, Anang; KOSINSKI, Aaron et al.Bioorganic & medicinal chemistry letters (Print). 2008, Vol 18, Num 9, pp 2883-2885, issn 0960-894X, 3 p.Article

Activity of piperaquine and other 4-aminoquinoline antiplasmodial drugs against chloroquine-sensitive and resistant blood-stages of Plasmodium falciparum role of β-haematin inhibition and drug concentration in vacuolar water-and lipid-phasesWARHURST, David C; CRAIG, John C; ADAGU, Ipemida S et al.Biochemical pharmacology. 2007, Vol 73, Num 12, pp 1910-1926, issn 0006-2952, 17 p.Article

Chemical genetics of Plasmodium falciparumGUIGUEMDE, W. Armand; SHELAT, Anang A; JIMENEZ-DIAZ, Maria B et al.Nature (London). 2010, Vol 465, Num 7296, pp 311-315, issn 0028-0836, 5 p.Article

Synthesis of Artemiside and Its Effects in Combination with Conventional Drugs against Severe Murine MalariaJIN GUO; GUIGUEMDE, Armand W; BENTURA-MARCIANO, Annael et al.Antimicrobial agents and chemotherapy. 2012, Vol 56, Num 1, pp 163-173, issn 0066-4804, 11 p.Article

Structure-Guided Development of Selective TbcatB InhibitorsMALLARI, Jeremy P; SHELAT, Anang A; KOSINSKI, Aaron et al.Journal of medicinal chemistry (Print). 2009, Vol 52, Num 20, pp 6489-6493, issn 0022-2623, 5 p.Article

Rational design of a nonpeptide general chemical scaffold for reversible inhibition of PDZ domain interactionsFUJII, Naoaki; HARESCO, Jose J; NOVAK, Kathleen A. P et al.Bioorganic & medicinal chemistry letters (Print). 2007, Vol 17, Num 2, pp 549-552, issn 0960-894X, 4 p.Article

Structure-activity relationship study of 9-aminoacridine compounds in scrapie-infected neuroblastoma cellsMAY, Barnaby C. H; WITKOP, Juanita; SHERRILL, John et al.Bioorganic & medicinal chemistry letters (Print). 2006, Vol 16, Num 18, pp 4913-4916, issn 0960-894X, 4 p.Article

Improvement of Pharmacological Properties of Irreversible Thyroid Receptor Coactivator Binding InhibitorsJONG YEON HWANG; AMOLD, Leggy A; FANGYI ZHU et al.Journal of medicinal chemistry (Print). 2009, Vol 52, Num 13, pp 3892-3901, issn 0022-2623, 10 p.Article

Inactivation of the p53 pathway in retinoblastomaLAURIE, Nikia A; DONOVAN, Stacy L; JOHNSON, Dianna et al.Nature (London). 2006, Vol 444, Num 7115, pp 61-66, issn 0028-0836, 6 p.Article

MDM2 antagonist nutlin-3a reverses mitoxantrone resistance by inhibiting breast cancer resistance protein mediated drug transportFAN ZHANG; THROM, Stacy L; MURLEY, Laura L et al.Biochemical pharmacology. 2011, Vol 82, Num 1, pp 24-34, issn 0006-2952, 11 p.Article

Whole-Body Physiologically Based Pharmacokinetic Model for Nutlin-3a in Mice after Intravenous and Oral AdministrationFAN ZHANG; TAGEN, Michael; FANGYI ZHU et al.Drug metabolism and disposition. 2011, Vol 39, Num 1, pp 15-21, issn 0090-9556, 7 p.Article

Benzoflavone activators of the cystic fibrosis transmembrane conductance regulator: Towards a pharmacophore model for the nucleotide-binding domainSPRINGSTEEL, Mark F; GALIETTA, Luis J. V; KIPLIN GUY, R et al.Bioorganic & medicinal chemistry. 2003, Vol 11, Num 18, pp 4113-4120, issn 0968-0896, 8 p.Article